[Orthogonal experiments to select spraying granulation technique for Baoshen granules]

Zhongguo Zhong Yao Za Zhi. 2005 Oct;30(20):1587-8.
[Article in Chinese]

Abstract

Objective: To raise the end-product and economical efficiency of spraying granulation, we demand screening preparation technique.

Method: Adopting newly spraying granulation technique, taking extracting technique, adhesive material, temperature of exit and entry,and the matching of accessories as inspecting factors, two levels of each factors, end-product as inspecting marker, we selected the best Baoshen granules preparation technique by orthogonal design.

Result: Among the 4 factors, adhesive material is most notable, next is temperature of exit and entry, the other two is of little importance.

Conclusion: The optimum spraying granulation technique of Baoshen granules is A2B1C2D1.

Publication types

  • English Abstract

MeSH terms

  • Adhesives
  • Cyclodextrins
  • Drug Combinations
  • Drug Compounding / methods*
  • Drugs, Chinese Herbal / administration & dosage*
  • Drugs, Chinese Herbal / isolation & purification
  • Plants, Medicinal* / chemistry
  • Powders
  • Temperature

Substances

  • Adhesives
  • Cyclodextrins
  • Drug Combinations
  • Drugs, Chinese Herbal
  • Powders