Localizations of N- and R-cadherins in dorsal root ganglia and lumbar spinal cord of the chick were immunocytochemically examined. As a result, N- and R-cadherin appeared to be co-localized on plasmalemma of neurons in dorsal root ganglia that were in contact with satellite cells, whereas there was no expression in neurons of the ventral horn. These findings indicate the possibility that expression pattern of cadherins in the peripheral neuron differs with its functional property (e.g. sensory or motor).