Salmonella transcriptomics: relating regulons, stimulons and regulatory networks to the process of infection

Arthur Thompson; Gary Rowley; Mark Alston; Vittoria Danino; Jay C D Hinton

doi:10.1016/j.mib.2005.12.010

Salmonella transcriptomics: relating regulons, stimulons and regulatory networks to the process of infection

Curr Opin Microbiol. 2006 Feb;9(1):109-16. doi: 10.1016/j.mib.2005.12.010. Epub 2006 Jan 18.

Authors

Arthur Thompson¹, Gary Rowley, Mark Alston, Vittoria Danino, Jay C D Hinton

Affiliation

¹ Molecular Microbiology Group, Institute of Food Research, Norwich Research Park, Norwich, NR4 7UA, UK. arthur.thompson@bbsrc.ac.uk

PMID: 16413221
DOI: 10.1016/j.mib.2005.12.010

Abstract

The advent of Salmonella transcriptomics has heralded a new era for gene expression analysis of this formidable intracellular pathogen. Increasing numbers of Salmonella transcriptomic datasets will contribute to the comprehensive definition of regulons, stimulons and regulatory networks. This task has highlighted the need for sophisticated computational techniques to describe regulatory interactions.

Publication types

Research Support, Non-U.S. Gov't
Review

MeSH terms

Adaptation, Physiological / genetics
Animals
Computational Biology / methods
Gene Expression Profiling
Gene Expression Regulation, Bacterial*
Humans
Oligonucleotide Array Sequence Analysis
RNA, Bacterial / analysis
RNA, Messenger / analysis
Regulon*
Salmonella / genetics*
Salmonella Infections / microbiology*
Salmonella Infections, Animal / microbiology
Transcription, Genetic*

Substances

RNA, Bacterial
RNA, Messenger