[Alkaloids from the root of Lindera angustifolia]

Yao Xue Xue Bao. 2005 Oct;40(10):931-4.
[Article in Chinese]

Abstract

Aim: To study the alkaloid constituents of the root of Lindera angustifolia Cheng.

Methods: The constituents were isolated and purified by column chromatography and the structures were characterized by spectral analysis.

Results: Seven aporphine alkaloids, laurotetanine (I), N-methyllaurotetanine (II), boldine (III), isoboldine (IV), norboldine (V), N-ethoxycarbonyllaurotetanine (VII) and a quaternary isoquinoline alkaloid, magnocurarine (VI), were isolated and identified. The structure of VII was further identified by semi-synthesis with I as starting material.

Conclusion: All compounds were obtained from this plant for the first time and compound VII was found as a naturally occurring compound for the first time.

MeSH terms

  • Alkaloids / chemistry
  • Alkaloids / isolation & purification*
  • Aporphines / chemistry
  • Aporphines / isolation & purification*
  • Isoquinolines / chemistry
  • Isoquinolines / isolation & purification
  • Lindera / chemistry*
  • Molecular Conformation
  • Molecular Structure
  • Plant Roots / chemistry
  • Plants, Medicinal / chemistry*

Substances

  • Alkaloids
  • Aporphines
  • Isoquinolines
  • magnocurarine
  • boldine
  • isoboldine
  • laurotetanine