Gallium(III) complexes of methyl pyropheophorbide-a as synthetic models for investigation of diastereomerically controlled axial ligation towards chlorophylls

Shin-Ichi Sasaki; Tadashi Mizoguchi; Hitoshi Tamiaki

doi:10.1016/j.bmcl.2005.11.081

Gallium(III) complexes of methyl pyropheophorbide-a as synthetic models for investigation of diastereomerically controlled axial ligation towards chlorophylls

Bioorg Med Chem Lett. 2006 Mar 1;16(5):1168-71. doi: 10.1016/j.bmcl.2005.11.081. Epub 2006 Jan 5.

Authors

Shin-Ichi Sasaki¹, Tadashi Mizoguchi, Hitoshi Tamiaki

Affiliation

¹ Department of Bioscience and Biotechnology, Faculty of Science and Engineering, Ritsumeikan University, Kusatsu, Shiga 525-8577, Japan.

PMID: 16403627
DOI: 10.1016/j.bmcl.2005.11.081

Abstract

Gallium(III) chlorins possessing a series of axial ligands were synthesized as model compounds of natural chlorophylls. A pair of diastereomers arising from the fifth axial coordination onto the asymmetric chlorin pi-macrocycle could be discriminated in a solution by both (1)H- and (13)C NMR spectroscopies.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Chlorophyll / chemistry*
Gallium / chemistry*
Ligands
Magnetic Resonance Spectroscopy
Models, Chemical
Molecular Structure
Porphyrins / chemical synthesis
Porphyrins / chemistry*
Stereoisomerism

Substances

Ligands
Porphyrins
pyropheophorbide-a methylester
Chlorophyll
Gallium