Upward gaze-evoked nystagmus with organoarsenic poisoning

Neurology. 2006 Jan 10;66(1):131-2. doi: 10.1212/01.wnl.0000191396.40700.eb.

Abstract

The authors report assessment of abnormal ocular movements in three patients after organoarsenic poisoning from diphenylarsinic acid. The characteristic and principal sign is upward gaze-evoked nystagmus. Moreover, vertical gaze holding impairment was shown by electronystagmography on direct current recording.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Adult
  • Arsenic Poisoning / complications*
  • Arsenic Poisoning / diagnosis
  • Arsenic Poisoning / physiopathology*
  • Arsenicals / adverse effects
  • Chemical Warfare Agents / adverse effects
  • Female
  • Fixation, Ocular / drug effects
  • Fixation, Ocular / physiology
  • Humans
  • Japan
  • Magnetic Resonance Imaging
  • Mesencephalon / drug effects
  • Mesencephalon / pathology
  • Mesencephalon / physiopathology
  • Nystagmus, Pathologic / chemically induced*
  • Nystagmus, Pathologic / diagnosis
  • Nystagmus, Pathologic / physiopathology*
  • Oculomotor Muscles / innervation
  • Oculomotor Muscles / physiopathology
  • Oculomotor Nerve / drug effects
  • Oculomotor Nerve / pathology
  • Oculomotor Nerve / physiopathology
  • Water Pollutants, Chemical / adverse effects

Substances

  • Arsenicals
  • Chemical Warfare Agents
  • Water Pollutants, Chemical
  • diphenylarsinic acid