Utility of the VITEK 2 Advanced Expert System for identification of extended-spectrum beta-lactamase production in Enterobacter spp

Mitchell J Schwaber; Shiri Navon-Venezia; Inna Chmelnitsky; Azita Leavitt; David Schwartz; Yehuda Carmeli

doi:10.1128/JCM.44.1.241-243.2006

Utility of the VITEK 2 Advanced Expert System for identification of extended-spectrum beta-lactamase production in Enterobacter spp

J Clin Microbiol. 2006 Jan;44(1):241-3. doi: 10.1128/JCM.44.1.241-243.2006.

Authors

Mitchell J Schwaber¹, Shiri Navon-Venezia, Inna Chmelnitsky, Azita Leavitt, David Schwartz, Yehuda Carmeli

Affiliation

¹ Division of Epidemiology, Tel Aviv Sourasky Medical Center, Israel. mitchells@tasmc.health.gov.il

Abstract

Forty clinical isolates of Enterobacter spp. were identified as extended-spectrum beta-lactamase (ESBL) producers by disk diffusion. The VITEK 2 Advanced Expert System (AES) identified the ESBL phenotype in only 25 isolates (62.5%), and erroneously reported cephalosporin susceptibility in 11 isolates (28%). Refinements in the AES are required in order to improve ESBL detection in Enterobacter.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Enterobacter / enzymology
Enterobacter / isolation & purification*
Enterobacteriaceae Infections / classification
Enterobacteriaceae Infections / microbiology
Humans
Reagent Kits, Diagnostic*
beta-Lactamases / metabolism*

Substances

Reagent Kits, Diagnostic
beta-Lactamases