Famoxadone is a recent oxazolidinedione fungicide widely used in viticulture and in Integrated Pest Management strategies. In this work, after a simple and fast liquid-liquid extraction (LLE), two new gas chromatographic methods were developed to analyze famoxadone residues in grapes and wines, one with electron-capture detection (GC-ECD) and the other with mass spectrometry (GC-MS). Global uncertainties for validation parameters of both methods were compared. Limits of detection (LODs) were 0.06 and 0.02 mg/L, precision was not above 11.7 and 6.8% and recoveries were, on average, 103%+/-12 and 96%+/-12, respectively, for the GC-ECD and GC-MS methods. Similar expanded uncertainties in the range from 0.25 to 1.00 mg/L were below 35%, with increasing values for lower levels of famoxadone. GC-MS method had a lower LOD and a lower uncertainty if compared with the GC-ECD method.