Biosynthesis of the heat-shock protein 90 inhibitor geldanamycin: new insight into the formation of the benzoquinone moiety

Chembiochem. 2006 Feb;7(2):246-8. doi: 10.1002/cbic.200500441.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antibiotics, Antineoplastic / biosynthesis*
  • Antibiotics, Antineoplastic / chemistry
  • Benzoquinones / chemistry
  • Benzoquinones / metabolism
  • HSP90 Heat-Shock Proteins / antagonists & inhibitors*
  • Lactams, Macrocyclic
  • Molecular Structure
  • Quinones / chemistry
  • Quinones / metabolism*

Substances

  • Antibiotics, Antineoplastic
  • Benzoquinones
  • HSP90 Heat-Shock Proteins
  • Lactams, Macrocyclic
  • Quinones
  • geldanamycin