Abstract
Tea catechins are known to be epimerized by heat treatment. The effect of heat-epimerized tea catechins on serum cholesterol concentration was compared with that of green tea catechins. Our observations strongly suggest that both tea catechins and heat-epimerized tea catechins lower serum cholesterol concentration by inhibiting cholesterol absorption in the intestine. There was no differential effect between the two catechin preparations.
MeSH terms
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Animals
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Anticholesteremic Agents*
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Body Weight / drug effects
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Catechin / chemistry*
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Catechin / pharmacology*
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Cholesterol / blood*
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Cholesterol, Dietary / pharmacology*
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Cholesterol, HDL / blood
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Eating / drug effects
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Feces / chemistry
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Hot Temperature
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Intestinal Absorption / drug effects
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Lipids / blood
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Male
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Rats
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Rats, Sprague-Dawley
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Stereoisomerism
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Tea / chemistry*
Substances
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Anticholesteremic Agents
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Cholesterol, Dietary
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Cholesterol, HDL
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Lipids
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Tea
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Catechin
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Cholesterol