[Toxocariasis mimicking liver tumor]

Presse Med. 2005 Dec 17;34(22 Pt 1):1715-6. doi: 10.1016/s0755-4982(05)84257-5.
[Article in French]

Abstract

Introduction: Toxocariasis is a common helminth infection that causes visceral larva migrans in humans. It has a wide and varied clinical spectrum.

Case: A 60-year-old woman consulted after 6 months of recurrent biliary pain with fever. Laboratory tests showed moderate disturbance of liver enzymes and hypereosinophilia (10 400/mm3). Imaging studies revealed a pseudotumor in hepatic segment IV, hyperechoic in abdominal ultrasound and low density in computed tomography. The diagnostic conclusion after ultrasound-guided liver biopsy was unspecific granulomatous hepatitis and eosinophilic infiltrate. The course of the antibody titer to Toxocara canis finally resulted in a diagnosis of Toxocara infection. Outcome was good following treatment with diethylcarbamazine.

Discussion: Some clinical features of liver toxocariasis can mimic tumors and may be interpreted histologically as granulomatous hepatitis, eosinophilic infiltrate of the hepatic portal vein, and/or necrotizing eosinophilic abscesses. Treatment is not yet well codified, but the symptomatic forms call for albendazole or diethylcarbamazine.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Diagnosis, Differential
  • Diethylcarbamazine / therapeutic use
  • Eosinophilia / parasitology
  • Female
  • Filaricides / therapeutic use
  • Humans
  • Liver Neoplasms / diagnosis
  • Middle Aged
  • Toxocariasis / diagnosis*
  • Toxocariasis / drug therapy

Substances

  • Filaricides
  • Diethylcarbamazine