B-mode compound imaging in mice

Ultrasound Med Biol. 2006 Jan;32(1):29-32. doi: 10.1016/j.ultrasmedbio.2005.08.011.

Abstract

Cross-sectional B-mode images were obtained from a dead mouse for a 360 degrees scan around the mouse using a 12-MHz linear array. For each cross-section, a set of aligned images was obtained after rotation about the isocenter, which were added to produce a single compound image. The compound images demonstrated a substantial improvement over single B-mode images, with uniform image quality, low noise and improved visualization of structures. This technique may be of interest in forming the basis for a new 3-D in vivo technique in the abdomen and pelvic regions, providing high-quality ultrasound images that are not dependent on operator skill. A further development worth pursuing for improved spatial resolution is reconstruction-based tomography.

MeSH terms

  • Animals
  • Imaging, Three-Dimensional / methods
  • Mice
  • Models, Animal*
  • Rotation
  • Spine / diagnostic imaging
  • Ultrasonography / methods*
  • Ultrasonography / standards