Autonomic features in cluster headache. Exploratory factor analysis

J Headache Pain. 2005 Feb;6(1):20-3. doi: 10.1007/s10194-005-0146-5. Epub 2005 Jan 25.

Abstract

The objective is to identify the pathogenesis of each autonomic manifestation in cluster headache (CH). Through a deductive statistics method (factor analysis) we analysed the type of autonomic symptoms reported by 157 CH patients. Three principal components were identified in the analysis: parasympathetic activation (lacrimation, conjunctival injection and rhinorrhoea), sympathetic defect (miosis and ptosis) and parasympathetic mediated effect (nasal congestion, eyelid oedema and forehead sweating). This work suggests that there are three different mechanisms underlying autonomic manifestations in CH.

MeSH terms

  • Adult
  • Autonomic Nervous System Diseases / epidemiology
  • Autonomic Nervous System Diseases / physiopathology*
  • Blepharoptosis / etiology
  • Blepharoptosis / physiopathology
  • Cluster Headache / physiopathology*
  • Conjunctiva / blood supply
  • Conjunctiva / innervation
  • Conjunctiva / physiopathology
  • Edema / etiology
  • Edema / physiopathology
  • Female
  • Humans
  • Hyperhidrosis / etiology
  • Hyperhidrosis / physiopathology
  • Lacrimal Apparatus Diseases / etiology
  • Lacrimal Apparatus Diseases / physiopathology
  • Male
  • Middle Aged
  • Miosis / etiology
  • Miosis / physiopathology
  • Nasal Mucosa / innervation
  • Nasal Mucosa / metabolism
  • Nasal Mucosa / physiopathology
  • Parasympathetic Nervous System / physiopathology*
  • Prevalence
  • Principal Component Analysis
  • Sympathetic Nervous System / physiopathology*