[Study of beta-turns in globular proteins]

Biofizika. 2005 Nov-Dec;50(6):1150-2.
[Article in Russian]

Abstract

The formation of beta-turns in globular proteins has been studied by the method of molecular mechanics. Statistical method of discriminant analysis was applied to calculate energy components and sequences of oligopeptide segments, and after this prediction of I type beta-turns has been drawn. The accuracy of true positive prediction is 65%. Components of conformational energy considerably affecting beta-turn formation were delineated. There are torsional energy, energy of hydrogen bonds, and van der Waals energy.

Publication types

  • English Abstract

MeSH terms

  • Hydrogen Bonding
  • Oligopeptides / chemistry*
  • Protein Structure, Secondary
  • Sequence Analysis, Protein / methods

Substances

  • Oligopeptides