Abstract
To test whether indomethacin prophylaxis has sex-mediated effects on severe intraventricular hemorrhage (grade III and IV) and on long-term outcomes in extremely-low-birth-weight infants. A secondary analysis was performed in the entire "Trial of Indomethacin Prophylaxis in Preterms study" cohort. The results suggest a weak differential treatment effect of indomethacin by sex.
Publication types
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Comparative Study
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Research Support, N.I.H., Extramural
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Research Support, Non-U.S. Gov't
MeSH terms
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Anti-Inflammatory Agents, Non-Steroidal / therapeutic use*
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Cerebral Ventricles*
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Developmental Disabilities / prevention & control*
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Female
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Humans
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Indomethacin / therapeutic use*
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Infant, Newborn
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Infant, Premature*
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Infant, Very Low Birth Weight*
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Intracranial Hemorrhages / prevention & control*
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Male
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Sex Factors
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Treatment Outcome
Substances
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Anti-Inflammatory Agents, Non-Steroidal
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Indomethacin