Intrauterine hemodynamic change in TTTS: the alterations in the inferior vena cava waveform in the donor fetus

Abstract

Background: Significant hemodynamic changes are commonly observed in both fetuses in twin-twin transfusion syndrome.

Methods and results: We describe two donor fetus cases in twin-twin transfusion syndrome associated with abnormal waveform patterns in the inferior vena cava after therapeutic amnioreduction. Subsequent echocardiographic examinations demonstrated progressive deterioration of the cardiac function in the recipient fetuses.

Conclusions: We suggest that alterations in the inferior vena cava waveform in the donor fetuses may contribute to the accurate prediction of deterioration in fetal circulation after amnioreduction.