Newborn thyrotropin screening confirms iodine deficiency in Latvia

Eur J Clin Nutr. 2006 May;60(5):688-90. doi: 10.1038/sj.ejcn.1602364.

Abstract

Objective and setting: The national neonatal thyrotropin (TSH) screening data for 2000-2002 were analysed to assess the extent and severity of iodine deficiency in Latvia.

Results: Elevated newborn TSH (>5 mIU/l) decreased from 16.5 to 10.4% and 8.4% in 2000, 2001 and 2002, respectively. For each year and in all regions, the prevalence of elevated newborn TSH was above the cut-off level indicative for a public health problem. A positive correlation (r=0.82, P<0.05) existed between elevated newborn TSH and low urinary iodine excretion among a nationwide sample of school children in 2000.

Conclusion: Latvia is iodine deficient, putting each new generation at risk of preventable brain damage.

MeSH terms

  • Biomarkers / blood
  • Biomarkers / urine
  • Cognition Disorders / diagnosis
  • Cognition Disorders / epidemiology
  • Cognition Disorders / etiology
  • Female
  • Humans
  • Infant Nutrition Disorders / complications
  • Infant Nutrition Disorders / diagnosis*
  • Infant Nutrition Disorders / epidemiology
  • Infant, Newborn
  • Iodine / deficiency*
  • Iodine / urine
  • Latvia / epidemiology
  • Male
  • Mass Screening*
  • Prevalence
  • Rural Population
  • Seroepidemiologic Studies
  • Thyrotropin / blood*

Substances

  • Biomarkers
  • Thyrotropin
  • Iodine