Rehabilitation and health care researchers are increasingly called upon to examine contemporary disability issues from an interdisciplinary perspective. Therefore, the purpose of this article is to (a) borrow from the counseling literature to introduce the working alliance, a model developed by Bordin [1] to facilitate positive therapeutic relationships; and (b) to discuss its application to interdisciplinary research. The authors, who represent the fields of nursing, rehabilitation, and health communication, describe characteristics of the working alliance and draw upon their experiences to illustrate the key components of effective working alliances (bonds, goals, and tasks). We also introduce strategies for resolving disagreements and conclude the article with a discussion regarding the multiple rewards that can be acquired from interdisciplinary research.