PCDD/F and PCB transfer to milk in goats exposed to a long-term intake of contaminated hay

Chemosphere. 2006 Jul;64(4):650-7. doi: 10.1016/j.chemosphere.2005.10.052. Epub 2005 Dec 9.

Abstract

The purpose of this study was to determine the feed to milk transfer of 17 PCDD/Fs and 18 PCBs in goats exposed to a 10-week long-term intake of contaminated hay collected in the vicinity of a hazardous municipal waste incinerator. The sum of PCDD/Fs and PCBs WHO-I-TEQ was found to be higher than 3 ng kg(-1) of milk fat after the first experimental week. Carry-over rates (CORs) of PCDD/Fs and PCBs could be established at steady state conditions for each compound studied. For PCDD/Fs, 2,3,7,8-TCDD appeared as the compound having the highest COR (38.8%). Within dioxin-like-PCBs the highest COR were found at a similar level (higher than 80%) for PCBs 105, 118 and 157. Concerning indicator-PCBs, COR ranged from 5% (PCB 101) to more than 40% (PCBs 118, 153 and 180). The intensity of this transfer appeared to be a function of physico-chemical properties (chlorination or logK(ow)) of the molecules and their metabolic behaviour.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animal Feed / analysis*
  • Animals
  • Benzofurans / analysis
  • Benzofurans / pharmacokinetics
  • Dibenzofurans, Polychlorinated
  • Environmental Pollutants / analysis*
  • Environmental Pollutants / pharmacokinetics
  • Female
  • Food Contamination*
  • Goats
  • Maternal Exposure*
  • Milk / chemistry*
  • Polychlorinated Biphenyls / analysis
  • Polychlorinated Biphenyls / pharmacokinetics
  • Polychlorinated Dibenzodioxins / analogs & derivatives
  • Polychlorinated Dibenzodioxins / analysis
  • Polychlorinated Dibenzodioxins / pharmacokinetics
  • Time Factors

Substances

  • Benzofurans
  • Dibenzofurans, Polychlorinated
  • Environmental Pollutants
  • Polychlorinated Dibenzodioxins
  • Polychlorinated Biphenyls