Analog frontend for multichannel neuronal recording system with spike and LFP separation

Yevgeny Perelman; Ran Ginosar

doi:10.1016/j.jneumeth.2005.09.017

Analog frontend for multichannel neuronal recording system with spike and LFP separation

J Neurosci Methods. 2006 May 15;153(1):21-6. doi: 10.1016/j.jneumeth.2005.09.017. Epub 2005 Dec 6.

Authors

Yevgeny Perelman¹, Ran Ginosar

Affiliation

¹ VLSI Systems Research Center, Department of Electrical Engineering, Technion-Israel Institute of Technology, Haifa 32000, Israel. perelman@tx.technion.ac.il

PMID: 16337276
DOI: 10.1016/j.jneumeth.2005.09.017

Abstract

A 0.35microm CMOS integrated circuit for multi-channel neuronal recording with twelve true-differential channels, band separation and digital offset calibration is presented. The measured signal is separated into a low-frequency local field potential and high-frequency spike data. Digitally programmable gains of up to 60 and 80 dB for the local field potential and spike bands are provided. DC offsets are compensated on both bands by means of digitally programmable DACs. Spike band is limited by a second order low-pass filter with digitally programmable cutoff frequency. The IC has been fabricated and tested. 3microV input referred noise on the spike data band was measured.

Publication types

Evaluation Study

MeSH terms

Action Potentials / physiology*
Amplifiers, Electronic*
Analog-Digital Conversion*
Equipment Design
Equipment Failure Analysis
Membrane Potentials / physiology*
Microcomputers*
Neurons / physiology*
Signal Processing, Computer-Assisted / instrumentation