Comparison of the avidity index method and the serologic testing algorithm for recent human immunodeficiency virus (HIV) seroconversion, two methods using a single serum sample for identification of recent HIV infections

Elisa Martró; Barbara Suligoi; Victoria González; Vincenzo Bossi; Anna Esteve; Joanne Mei; Vicenç Ausina

doi:10.1128/JCM.43.12.6197-6199.2005

Comparison of the avidity index method and the serologic testing algorithm for recent human immunodeficiency virus (HIV) seroconversion, two methods using a single serum sample for identification of recent HIV infections

J Clin Microbiol. 2005 Dec;43(12):6197-9. doi: 10.1128/JCM.43.12.6197-6199.2005.

Authors

Elisa Martró¹, Barbara Suligoi, Victoria González, Vincenzo Bossi, Anna Esteve, Joanne Mei, Vicenç Ausina

Affiliation

¹ Microbiology Service. Hospital Universitari Germans Trias i Pujol. Ctra de Canyet, s/n 08916 Badalona, Spain.

Abstract

A study was designed to compare an avidity index method to the serologic testing algorithm for recent human immunodeficiency virus (HIV) seroconversion (STARHS) for the detection of recent HIV infection. One hundred sixty HIV-positive sera were tested. Both techniques performed similarly in identifying recent infections, although STARHS tended to misclassify more individuals that had long-standing infection as being recently infected.

Publication types

Comparative Study
Evaluation Study
Research Support, Non-U.S. Gov't

MeSH terms

Algorithms*
Antibody Affinity*
HIV Antibodies / blood*
HIV Infections / diagnosis*
HIV Infections / immunology*
HIV Seropositivity / diagnosis*
Humans

Substances

HIV Antibodies