Introduction: Familial occurrence of progressive systemic sclerosis is unusual. The occurrence of conjugal scleroderma is exceptional.
Exegesis: We report here a case of systemic sclerosis in a wife and husband who both developed the onset of illness within a 10-year period. Solvent exposure was noted.
Conclusion: The etiology of systemic sclerosis remains unknown. Environmental factors may play role in its pathogenesis.