N(3),5'-cycloxanthosine, the first natural occurrence of a cyclonucleoside

J Nat Prod. 2005 Nov;68(11):1689-91. doi: 10.1021/np0502692.

Abstract

An Eryus sp. of marine sponge from the Great Australian Bight has yielded the first reported natural occurrence of a cyclonucleoside, N(3),5'-cycloxanthosine. The structure of N(3),5'-cycloxanthosine was confirmed by detailed spectroscopic analysis and total synthesis.

MeSH terms

  • Animals
  • Australia
  • Molecular Structure
  • Nuclear Magnetic Resonance, Biomolecular
  • Porifera / chemistry*
  • Ribonucleosides / chemical synthesis
  • Ribonucleosides / chemistry
  • Ribonucleosides / isolation & purification*
  • Tryptophan / analogs & derivatives*
  • Tryptophan / chemical synthesis
  • Tryptophan / chemistry
  • Tryptophan / isolation & purification
  • Xanthines / chemical synthesis
  • Xanthines / chemistry
  • Xanthines / isolation & purification*

Substances

  • N(3),5'-cycloxanthosine
  • Ribonucleosides
  • Xanthines
  • Tryptophan
  • xanthosine