Abstract
The case report of a 2 year old boy with steroid refractory DBA, treated with allogeneic PBSCT from an HLA matched sibling is presented. Anti-IL2 receptor antibody Daclizumab was used as a prophylaxis for graft versus host disease (GvHD). Complete recovery without any evidence of GvHD ensued.
MeSH terms
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Acute Disease
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Anemia, Diamond-Blackfan / drug therapy
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Anemia, Diamond-Blackfan / surgery*
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Antibodies, Monoclonal / therapeutic use*
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Antibodies, Monoclonal, Humanized
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Daclizumab
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Follow-Up Studies
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Glucocorticoids / therapeutic use*
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Graft vs Host Disease / blood
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Graft vs Host Disease / prevention & control*
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Humans
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Immunoglobulin G / therapeutic use*
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Immunosuppressive Agents / therapeutic use*
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Infant
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Male
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Peripheral Blood Stem Cell Transplantation*
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Receptors, Interleukin-2 / antagonists & inhibitors*
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Receptors, Interleukin-2 / blood
Substances
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Antibodies, Monoclonal
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Antibodies, Monoclonal, Humanized
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Glucocorticoids
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Immunoglobulin G
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Immunosuppressive Agents
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Receptors, Interleukin-2
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Daclizumab