Heat shock protein 90 inhibitors. A text book example of medicinal chemistry?

J Med Chem. 2005 Dec 1;48(24):7503-12. doi: 10.1021/jm050759r.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Antineoplastic Agents / chemical synthesis
  • Antineoplastic Agents / chemistry*
  • Benzoquinones
  • Drug Design*
  • HSP90 Heat-Shock Proteins / antagonists & inhibitors*
  • Humans
  • Lactams, Macrocyclic
  • Lactones / chemical synthesis
  • Lactones / chemistry
  • Macrolides
  • Quinones / chemical synthesis
  • Quinones / chemistry
  • Structure-Activity Relationship

Substances

  • Antineoplastic Agents
  • Benzoquinones
  • HSP90 Heat-Shock Proteins
  • Lactams, Macrocyclic
  • Lactones
  • Macrolides
  • Quinones
  • monorden
  • geldanamycin