Total synthesis of anthocyanidins via Heck reaction

Nat Prod Res. 2006 Jan;20(1):93-7. doi: 10.1080/14786410500059474.

Abstract

Anthocyanidin moiety was obtained by cyclization of a 2-hydroxychalcone prepared by the Heck approach to the synthesis of flavonoids. 1-(3,4-dimethoxyphenyl)-prop-2-en-1-one has been used as a coupling partner along with o-acetoxyiodobenzene in the Heck reaction.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anthocyanins / chemical synthesis*
  • Cyclization
  • Magnetic Resonance Spectroscopy

Substances

  • Anthocyanins