Slow diffusion by singlet state NMR spectroscopy

J Am Chem Soc. 2005 Nov 16;127(45):15744-8. doi: 10.1021/ja052897b.

Abstract

Small diffusion coefficients can be measured by using populations of singlet states that have a relaxation time constant, T(s), which can be much longer than the longitudinal relaxation time, T1. Spatial information can be encoded with pulsed field gradients in the manner of stimulated echo sequences. Singlet states can be excited via double-quantum coherences to enhance the efficiency of phase encoding and decoding.