Abstract
A new ulopyranose isolated from aqueous extract of roots and rhizomas of Psacalium peltatum has been determined to have hypoglycemic activity at doses of 100 mg/kg, comparable to that of tolbutamide and insulin in alloxan diabetic mice. The skeletal structure of the new compound was established by spectral analysis.
MeSH terms
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Acetylation
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Animals
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Asteraceae / chemistry*
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Blood Glucose / chemistry
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Carbohydrates / isolation & purification*
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Carbohydrates / pharmacology*
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Diabetes Mellitus, Experimental / blood
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Diabetes Mellitus, Experimental / drug therapy
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Hypoglycemic Agents / isolation & purification*
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Hypoglycemic Agents / pharmacology*
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Imino Pyranoses
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Magnetic Resonance Spectroscopy
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Male
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Mice
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Plant Extracts / chemistry
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Plant Roots / chemistry
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Spectrometry, Mass, Fast Atom Bombardment
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Spectrophotometry, Infrared
Substances
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Blood Glucose
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Carbohydrates
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Hypoglycemic Agents
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Imino Pyranoses
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Plant Extracts
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petalosa