Investigating neurocognitive features of hepatitis C virus infection in drug users: potential challenges and lessons learned from the HIV literature

Clin Infect Dis. 2005 Jul 1:41 Suppl 1:S45-9. doi: 10.1086/429495.

Abstract

Studies of neurocognition in drug users with hepatitis C virus (HCV) infection are urgently needed but face many challenges. We review similarities between human immunodeficiency virus (HIV) and HCV infection in their neurocognitive features, discuss challenges associated with research among drug users, advocate that the HIV literature can usefully inform studies of HCV, and review findings by our group on neurocognition among substance users with HIV and/or HCV infection.

Publication types

  • Comparative Study
  • Research Support, N.I.H., Extramural
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Adult
  • Brain / physiopathology*
  • Chicago
  • Cognition Disorders / etiology
  • Cognition Disorders / physiopathology
  • Cognition Disorders / psychology*
  • HIV Infections / complications
  • HIV Infections / physiopathology
  • HIV Infections / psychology*
  • Hepatitis C / complications
  • Hepatitis C / physiopathology
  • Hepatitis C / psychology*
  • Humans
  • Middle Aged
  • Research
  • Substance Abuse, Intravenous / complications
  • Substance Abuse, Intravenous / physiopathology
  • Substance Abuse, Intravenous / psychology*