Debonding of the stem-cement interface and damage accumulation in the cement mantle are basic events that contribute to the long-term failure of cemented hip reconstructions. In this work, a numerical study with these two processes coupled is presented. On the one hand, debonding of the stem-cement interface was simulated by means of a cohesive surface theory that was implemented into an interface finite element. This interface model includes a tensile-shear behavior law, the fatigue failure of the interface, and the friction evolution between both surfaces. On the other hand, damage accumulation in the cement was formulated through the theory of continuum damage mechanics, considering cement damage due to tension, creep under compression, crack closure effects, non-linear damage accumulation and cement residual stresses appearing during polymerisation. This methodology was applied to simulate and compare the degradation process of the cement and stem-cement interface in four different concepts of design: Exeter, Charnley, Elite Plus and ABG II stems. As the actual mechanical properties of the surface of each specific prosthesis are not known, we assumed the same for all of them, distinguishing between polished and matt surfaces. With this assumption, the predicted results showed that the debonding process is very different for each implant depending on the stem geometry. Lower cement deterioration was obtained for the Exeter and ABG II stems, while the lowest stem-cement interface debonding was produced in the Exeter and the Elite Plus stems.