Conversion of a carboxylesterase into a triacylglycerol lipase by a random mutation

Angew Chem Int Ed Engl. 2005 Nov 25;44(46):7553-7. doi: 10.1002/anie.200502461.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Carboxylesterase / antagonists & inhibitors
  • Carboxylesterase / chemistry*
  • Carboxylesterase / genetics*
  • Enzyme Activation / drug effects
  • Enzyme Inhibitors / pharmacology
  • Lipase / antagonists & inhibitors
  • Lipase / chemistry*
  • Lipase / genetics*
  • Mutagenesis
  • Mutation
  • Protein Conformation
  • Protein Structure, Tertiary
  • Structure-Activity Relationship

Substances

  • Enzyme Inhibitors
  • Carboxylesterase
  • Lipase