Abstract
The preparative and stereoselective synthesis (45- 50% overall yields, >50 g scale) of the key carbasugars 7a-d was achieved from D-ribose via stereoselective Grignard reaction and oxidative rearrangement as key reactions.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Alcohols / chemistry
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Catalysis
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Cyclopentanes / chemical synthesis*
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Cyclopentanes / chemistry*
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Models, Chemical
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Molecular Biology / methods*
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Nucleosides / chemistry*
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Oxygen / chemistry
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Ribose / chemistry
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Stereoisomerism
Substances
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3-hydroxymethylcyclopentenone
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Alcohols
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Cyclopentanes
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Nucleosides
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Ribose
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cyclopentenone
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Oxygen