Abstract
Factors contributing to the duration of a single convulsive seizure > 5 minutes were analyzed in 157 children. The medically treated episodes were compared with seizure episodes resolving without treatment (n = 27). Major differences were in age (p = 0.016) and etiology (p = 0.003), and the association between treatment delay and response became significant after 30 minutes when this was analyzed as a single variable (p = 0.003) in Cox regression analysis.
MeSH terms
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Administration, Rectal
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Anticonvulsants / administration & dosage*
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Anticonvulsants / adverse effects
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Benzodiazepines / administration & dosage
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Benzodiazepines / adverse effects
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Child, Preschool
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Clinical Protocols / standards*
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Disease Progression
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Early Diagnosis
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Epilepsy / drug therapy*
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Epilepsy / etiology
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Epilepsy / physiopathology
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Female
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Humans
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Infusion Pumps
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Male
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Phenobarbital / administration & dosage
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Phenobarbital / adverse effects
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Phenytoin / administration & dosage
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Phenytoin / adverse effects
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Phenytoin / analogs & derivatives
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Retrospective Studies
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Secondary Prevention
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Status Epilepticus / physiopathology
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Status Epilepticus / prevention & control*
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Thiopental / administration & dosage
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Thiopental / adverse effects
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Time Factors
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Treatment Outcome
Substances
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Anticonvulsants
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Benzodiazepines
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Phenytoin
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fosphenytoin
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Thiopental
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Phenobarbital