Improved method of the MALDI-TOF analysis of DNA with nanodot sample target plate

Chem Commun (Camb). 2005 Nov 14:(42):5340-2. doi: 10.1039/b507065a. Epub 2005 Sep 26.

Abstract

We report a new sample target plate for MALDI-TOF mass spectrometry made of SiO2 with 30 nm Pt dots for which a highly reproducible and improved DNA analysis was achieved.

MeSH terms

  • DNA / analysis*
  • DNA / chemistry
  • Nanotechnology / methods*
  • Silicon Dioxide / chemistry
  • Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization / methods*

Substances

  • Silicon Dioxide
  • DNA