Abstract
Research on the highly virulent and contagious, facultative intracellular bacterium Francisella tularensis has come into the limelight recently, but still little is known regarding its virulence mechanisms. This review summarizes recent studies on its intramacrophage survival mechanisms, some of which appear to be novel.
Publication types
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Research Support, N.I.H., Extramural
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Research Support, Non-U.S. Gov't
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Review
MeSH terms
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Animals
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Endothelial Cells / microbiology*
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Francisella tularensis / genetics
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Francisella tularensis / growth & development*
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Francisella tularensis / pathogenicity*
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Humans
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Macrophages / microbiology*
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Mice
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Tularemia / microbiology
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Virulence