Use of preclinical models to improve treatment of retinoblastoma

PLoS Med. 2005 Oct;2(10):e332. doi: 10.1371/journal.pmed.0020332. Epub 2005 Oct 25.

Abstract

Dyer and colleagues examine the most promising preclinical models that recapitulate the molecular, genetic, and cellular features of retinoblastoma.

Publication types

  • Review

MeSH terms

  • Animals
  • Antineoplastic Agents / pharmacology
  • Antineoplastic Agents / therapeutic use
  • Cell Death
  • Cell Proliferation
  • Clinical Trials as Topic
  • Disease Models, Animal*
  • Humans
  • Mice
  • Phenotype
  • Retinal Neoplasms / physiopathology*
  • Retinal Neoplasms / therapy*
  • Retinoblastoma / physiopathology*
  • Retinoblastoma / therapy*

Substances

  • Antineoplastic Agents