Abstract
A case--control study was conducted to evaluate the relationship between C481T and G590A polymorphisms of arylamine-N-acetyltransferase 2 and predisposition to atopic dermatitis in children. Double heterozygote 481C/T and 590G/A in girls is a factor of resistance to atopic dermatitis, especially in the absence of smoking-related effects.
MeSH terms
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Adolescent
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Alleles
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Amino Acid Substitution
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Arylamine N-Acetyltransferase / genetics*
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Case-Control Studies
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Child
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Child, Preschool
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DNA / blood
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DNA / genetics
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Dermatitis, Atopic / diagnosis
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Dermatitis, Atopic / epidemiology
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Dermatitis, Atopic / genetics*
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Female
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Gene Frequency
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Genetic Predisposition to Disease
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Glycine / metabolism
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Heterozygote
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Humans
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Incidence
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Infant
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Male
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Polymerase Chain Reaction
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Polymorphism, Genetic*
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Risk Factors
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Sex Factors
Substances
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DNA
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Arylamine N-Acetyltransferase
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NAT2 protein, human
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Glycine