High-resolution real-time spiral MRI for guiding vascular interventions in a rabbit model at 1.5 T

J Magn Reson Imaging. 2005 Nov;22(5):687-90. doi: 10.1002/jmri.20409.

Abstract

Purpose: To study the feasibility of a combined high spatial and temporal resolution real-time spiral MRI sequence for guiding coronary-sized vascular interventions.

Materials and methods: Eight New Zealand White rabbits (four normal and four with a surgically-created stenosis in the abdominal aorta) were studied. A real-time interactive spiral MRI sequence combining 1.1 x 1.1 mm(2) in-plane resolution and 189-msec total image acquisition time was used to image all phases of an interventional procedure (i.e., guidewire placement, balloon angioplasty, and stenting) in the rabbit aorta using coronary-sized devices on a 1.5 T MRI system.

Results: Real-time spiral MRI identified all rabbit aortic stenoses and provided high-temporal-resolution visualization of guide-wires crossing the stenoses in all animals. Angioplasty balloon dilatation and deployment of coronary-sized copper stents in the rabbit aorta were also successfully imaged by real-time spiral MRI.

Conclusion: Combining high spatial and temporal resolution with spiral MRI allows real-time MR-guided vascular intervention using coronary-sized devices in a rabbit model. This is a promising approach for guiding coronary interventions.

Publication types

  • Evaluation Study
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Aorta, Abdominal / pathology
  • Aorta, Abdominal / surgery
  • Aortic Valve Stenosis / pathology*
  • Aortic Valve Stenosis / surgery*
  • Artificial Intelligence
  • Computer Systems
  • Image Enhancement / methods*
  • Image Interpretation, Computer-Assisted / methods*
  • Imaging, Three-Dimensional / methods*
  • Rabbits
  • Reproducibility of Results
  • Sensitivity and Specificity
  • Surgery, Computer-Assisted / methods*
  • Vascular Surgical Procedures / methods*