Orthotopic transplantation of fresh ovarian cortex: a report of two cases

Fertil Steril. 2005 Oct;84(4):1018. doi: 10.1016/j.fertnstert.2005.06.011.

Abstract

Objective: To report two cases of orthotopic transplantation of fresh ovarian tissue.

Setting: Academic hospital.

Patient(s): Two patients with severe endometriosis, who underwent left oophorectomy for recurrent endometriosis.

Intervention(s): Ovarian cortex was reimplanted in the heterolateral orthotopic site.

Result(s): Biopsies of the grafted tissue were taken 3 months after reimplantation. Viable primordial follicles were found. The presence of a neovascular capillary network was demonstrated.

Conclusion(s): Reimplantation of fresh ovarian cortex allows the survival of primordial follicles and may represent an alternative method for the preservation of ovarian cortex when oophorectomy is mandatory.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Female
  • Humans
  • Ovariectomy / methods*
  • Ovary / surgery
  • Ovary / transplantation*
  • Tissue Transplantation
  • Transplantation, Autologous