Nickel-catalyzed alkylation of aldehydes with trialkylboranes

Koji Hirano; Hideki Yorimitsu; Koichiro Oshima

doi:10.1021/ol051917b

Nickel-catalyzed alkylation of aldehydes with trialkylboranes

Org Lett. 2005 Oct 13;7(21):4689-91. doi: 10.1021/ol051917b.

Authors

Koji Hirano¹, Hideki Yorimitsu, Koichiro Oshima

Affiliation

¹ Department of Material Chemistry, Graduate School of Engineering, Kyoto University, Kyoto-daigaku Katsura, Nishikyo-ku, Kyoto 615-8510, Japan.

PMID: 16209511
DOI: 10.1021/ol051917b

Abstract

[reaction: see text] Nickel-catalyzed alkylation of aldehydes with trialkylboranes proceeds smoothly in the presence of a catalytic amount of 5-allyl-1,2,3,4,5-pentamethyl-1,3-cyclopentadiene or an excess of cesium carbonate to afford the corresponding secondary alcohols.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Alcohols / chemical synthesis*
Alcohols / chemistry
Aldehydes / chemistry*
Alkylation
Boranes / chemistry*
Catalysis
Molecular Structure
Nickel / chemistry*

Substances

Alcohols
Aldehydes
Boranes
Nickel