Endarterectomy for symptomatic carotid stenosis. Review of the European and North American Symptomatic Carotid Surgery Trials

A P Gasecki; V C Hachinski; T Mendel; H T Barnett

Endarterectomy for symptomatic carotid stenosis. Review of the European and North American Symptomatic Carotid Surgery Trials

Nebr Med J. 1992 Jun;77(6):121-3.

Authors

A P Gasecki¹, V C Hachinski, T Mendel, H T Barnett

Affiliation

¹ Department of Clinical Neurological Sciences, University of Western Ontario University Hospital, London, Canada.

PMID: 1620265

Abstract

The recent results of two major multicenter trials, ECST (European Carotid Surgery Trialists') and NASCET (North American Symptomatic Carotid Endarterectomy Trial), show benefit of carotid endarterectomy for patients with recent (4-6 months), nondisabling, carotid distribution, cerebral ischemic events (hemispheric and retinal TIA or stroke) and ipsilateral severe (70-99%) carotid stenosis provided that perioperative mortality remains low. ECST, in addition, failed to demonstrate the benefit of surgery for patients with mild stenosis (0-29%). The comparisons between the studies in regards to methodology, measurements, and complications are discussed.

Publication types

Review

MeSH terms

Carotid Stenosis / surgery*
Cerebrovascular Disorders / surgery*
Endarterectomy, Carotid*
Europe
Follow-Up Studies
Humans
Ischemic Attack, Transient / surgery*
United States