A straightforward synthesis of 3-acylphospholes

Magali Clochard; Joanna Grundy; Bruno Donnadieu; François Mathey

doi:10.1021/ol051816d

A straightforward synthesis of 3-acylphospholes

Org Lett. 2005 Sep 29;7(20):4511-3. doi: 10.1021/ol051816d.

Authors

Magali Clochard¹, Joanna Grundy, Bruno Donnadieu, François Mathey

Affiliation

¹ UCR-CNRS Joint Research Chemistry Laboratory, Department of Chemistry, University of California Riverside, Riverside, California 92521-0403, USA.

PMID: 16178571
DOI: 10.1021/ol051816d

Abstract

[structure: see text] The reaction of 2,5-diphenylphospholide, first with acyl chlorides, then with tBuOK, provides a direct access to 3-acyl-2,5-diphenylphospholides via a 1H-, 2H-, 3H-phosphole equilibrium.