Kinetics of the thermal inactivation of the Lactococcus lactis bacteriophage P008

J Dairy Res. 2005 Aug;72(3):281-6. doi: 10.1017/S0022029905000725.

Abstract

The thermal resistance of the lactococcal bacteriophage P008 was investigated between 55 and 80 degrees C. Inactivation kinetics revealed an order of reaction above 1 and could be determined by a non-1st-order regression model. Phage inactivation was influenced by the medium (milk and Ca-M17-broth). Within the investigated temperature range, milk had a protective effect on phage P008. This was reflected in the rate constant and in the activation energy. Thermal phage inactivation studies reported in literature were re-analysed using non-1st-order regression. The obtained kinetic parameters showed that phage P008 belongs to the most heat resistant lactococcal phages investigated so far.

MeSH terms

  • Animals
  • Bacteriophages / physiology*
  • Hot Temperature*
  • Kinetics
  • Lactococcus lactis / virology*
  • Milk
  • Regression Analysis
  • Virus Inactivation*