Prevention and treatment of osteoporosis in chronically ill children

J Musculoskelet Neuronal Interact. 2005 Jul-Sep;5(3):262-72.

Abstract

Osteoporosis secondary to chronic disease in children has emerged as a major health issue. As the severity of a child's illness increases, so too does the number of factors affecting their bone health. Determinants of bone health in children include level of mobility, exposure to osteotoxic medication, nutritional status, calcium and vitamin D intake, chronic inflammation and pubertal development.

Publication types

  • Review

MeSH terms

  • Adolescent
  • Bone Density / drug effects
  • Bone Density / physiology*
  • Bone and Bones / drug effects
  • Bone and Bones / metabolism
  • Bone and Bones / physiopathology*
  • Child
  • Chronic Disease / rehabilitation*
  • Diphosphonates / therapeutic use
  • Glucocorticoids / adverse effects
  • Humans
  • Immobilization / physiology
  • Osteonecrosis / etiology
  • Osteonecrosis / physiopathology
  • Osteonecrosis / therapy
  • Osteoporosis / etiology
  • Osteoporosis / prevention & control*
  • Osteoporosis / therapy*
  • Puberty, Delayed / complications
  • Puberty, Delayed / physiopathology
  • Vitamin D Deficiency / etiology
  • Vitamin D Deficiency / physiopathology
  • Vitamin D Deficiency / prevention & control

Substances

  • Diphosphonates
  • Glucocorticoids