Abstract
In Bacillus cereus and other gram-positive bacteria the alternative sigma factor sigma(B) is an important regulator of the stress response. Deletion of the sigB gene generally leads to a stress-sensitive phenotype of vegetative cells. In this study, we describe the effect of the deletion of the sigB gene in B. cereus on spore properties. In particular, spores of the sigB deletion mutant showed a defect in germination upon exposure to the germinants alanine and inosine.
Publication types
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, Non-P.H.S.
MeSH terms
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Bacillus cereus / genetics
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Bacillus cereus / growth & development
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Bacillus cereus / physiology*
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Bacterial Proteins / genetics*
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Bacterial Proteins / physiology*
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Culture Media
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Gene Deletion*
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Gene Expression Regulation, Bacterial*
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Heat-Shock Response*
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Sigma Factor / genetics*
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Sigma Factor / physiology*
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Spores, Bacterial / physiology
Substances
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Bacterial Proteins
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Culture Media
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SigB protein, Bacteria
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Sigma Factor