ESI-MS studies on the mechanism of Pd0-catalyzed three-component tandem double addition-cyclization reaction

Hao Guo; Rong Qian; Yuanxi Liao; Shengming Ma; Yinlong Guo

doi:10.1021/ja052588l

ESI-MS studies on the mechanism of Pd0-catalyzed three-component tandem double addition-cyclization reaction

J Am Chem Soc. 2005 Sep 21;127(37):13060-4. doi: 10.1021/ja052588l.

Authors

Hao Guo¹, Rong Qian, Yuanxi Liao, Shengming Ma, Yinlong Guo

Affiliation

¹ State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 354 Fenglin Road, Shanghai 200032, P R China.

PMID: 16159302
DOI: 10.1021/ja052588l

Abstract

Four cationic palladium intermediates have been characterized by the high-resolution ESI-FTMS technology, on the basis of which a mechanism was proposed for the Pd0-catalyzed three-component tandem double addition cyclization of organic halides, 2-(2,3-allenyl)malonates, and imines.

MeSH terms

Catalysis
Cyclization
Imines / chemical synthesis*
Malonates / chemical synthesis*
Molecular Structure
Organometallic Compounds / chemistry*
Palladium / chemistry*
Spectrometry, Mass, Electrospray Ionization / methods*

Substances

Imines
Malonates
Organometallic Compounds
Palladium