Apoptosis of peripheral human blood lymphocytes induced by physical-chemical influences and generation of reactive oxygen species

Ann N Y Acad Sci. 2005 Jun:1048:449-50. doi: 10.1196/annals.1342.062.

Abstract

The sensitivity of peripheral blood lymphocytes of healthy people (blood donors) to induced apoptotic processes and reactive oxygen species production under physical-chemical influences was evaluated in vitro.

MeSH terms

  • Antineoplastic Agents / toxicity*
  • Apoptosis / drug effects*
  • Apoptosis / radiation effects*
  • Dose-Response Relationship, Drug
  • Dose-Response Relationship, Radiation
  • Humans
  • Lymphocytes / drug effects*
  • Lymphocytes / metabolism
  • Lymphocytes / radiation effects*
  • Microscopy, Fluorescence
  • Radiation, Ionizing
  • Reactive Oxygen Species / metabolism*
  • Temperature
  • Vidarabine / analogs & derivatives
  • Vidarabine / toxicity

Substances

  • Antineoplastic Agents
  • Reactive Oxygen Species
  • Vidarabine
  • fludarabine