Recurrent urinary tract infections--uropathogen incidence and drug sensitivity

Ann Univ Mariae Curie Sklodowska Med. 2004;59(2):275-83.

Abstract

The aim of the study was the retrospective analysis of the results of the drug sensitivity studies of bacterial species cultured from 681 urinary specimens collected from 79 children (12 boys and 67 girls) aged 0-18 years with recurrent urinary tract infection in a period from 1997 to 2001. Factors predisposing to recurrent urinary tract infections and the incidences of particular uropathogens were also analyzed. Escherichia coli (57.3%), Proteus spp. (15.6%) and Pseudomonas aeruginosa (9.1%) were the most frequent isolated pathogens. Reinfections and relapses of urinary tract infections were observed in 74.7% and 25.3% of the children, respectively. In some children etiologic variability of particular infection episodes were observed. In the majority of the children infection episodes were caused by one or two bacterial species and new infections differed from previous ones only in drug sensitivity. In 30 children vesicoureteral reflux was detected. Other anatomical abnormalities of urinary tract were revealed in 17 children. In 18 children, neurogenic bladder dysfunction was diagnosed. Urodynamics disclosed functional abnormalities in 48/55 children.

MeSH terms

  • Adolescent
  • Bacteria / drug effects
  • Bacteria / isolation & purification*
  • Child
  • Child, Preschool
  • Female
  • Humans
  • Infant
  • Infant, Newborn
  • Male
  • Microbial Sensitivity Tests
  • Recurrence
  • Retrospective Studies
  • Urinary Tract Infections / drug therapy*
  • Urinary Tract Infections / microbiology*