Activation of apoptosis as a mechanism of thymus involution during repeated immobilization

O B Tseilikman; S V Sibiryak; V E Tseilikman; N V Bubnov; A I Sinitskii; D A Sysakov

doi:10.1007/s10517-005-0204-7

Activation of apoptosis as a mechanism of thymus involution during repeated immobilization

Bull Exp Biol Med. 2005 Jan;139(1):32-3. doi: 10.1007/s10517-005-0204-7.

Authors

O B Tseilikman¹, S V Sibiryak, V E Tseilikman, N V Bubnov, A I Sinitskii, D A Sysakov

Affiliation

¹ South Ural State University, Chelyabinsk, Russia. vadimed@yandedex.ru

PMID: 16142269
DOI: 10.1007/s10517-005-0204-7

Abstract

Lymphopenia preceded involution of the thymus during daily immobilization for 1 h. Hypoplasia of the thymus was associated with induction of apoptosis.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Animals
Apoptosis*
Lymphopenia / etiology*
Rats
Restraint, Physical
Stress, Psychological / etiology
Stress, Psychological / pathology*
Thymus Gland / pathology*