Thoracic extradural paragangliomas: a case report and review of the literature

Spinal Cord. 2006 Feb;44(2):120-5. doi: 10.1038/sj.sc.3101796.

Abstract

Study design: Case report.

Objectives: To report on a case of paraganglioma presenting in an uncommon extradural thoracic localization.

Setting: Department of Neurosurgery, Florence, Italy.

Case report: A 43-year-old woman with a thoracic lesion extending into the extradural space along four levels, T(1)-T(4), presented with sudden spastic incomplete paraplegia and paresthesia at the lower limbs.

Results: The neoplasm was surgically resected 'en bloc' and histological findings corresponded to paraganglioma. One year after surgery, the patient was walking without assistance, a T(3)-T(4) hypoesthesia was still present and an magnetic resonance imaging (MRI) study showed no signs of focal recurrence.

Conclusions: The imaging features of thoracic paragangliomas may be misleading and an advanced malignant lesion could be primarily suspected; thus, a histological study is always needed. Total resection is the gold standard therapy. Owing to the risk of recurrence or multicentric growth, follow-up must be prolonged and accurate.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adult
  • Female
  • Humans
  • Paraganglioma / complications
  • Paraganglioma / diagnosis*
  • Paraganglioma / surgery*
  • Paraplegia / etiology
  • Paraplegia / prevention & control*
  • Paresthesia / etiology
  • Paresthesia / prevention & control*
  • Radiography
  • Recovery of Function
  • Spinal Cord Neoplasms / complications
  • Spinal Cord Neoplasms / diagnosis*
  • Spinal Cord Neoplasms / surgery*
  • Thoracic Vertebrae / diagnostic imaging
  • Thoracic Vertebrae / pathology
  • Thoracic Vertebrae / surgery
  • Treatment Outcome